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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Phosphatidylinositol (3,4)-bisphosphate ： ウィキペディア英語版 Phosphatidylinositol 3,4-bisphosphate Phosphatidylinositol (3,4)-bisphosphate (PtdIns(3,4)''P''2) is a minor phospholipid component of cell membranes, yet an important second messenger. The generation of PtdIns(3,4)''P''2 at the plasma membrane activates a number of important cell signaling pathways. PtdIns(3,4)''P''2 is dephophosphorylated by the phosphatase INPP4B on the 4 position of the inositol ring and by the TPTE (transmembrane phosphatases with tensin homology) family of phosphatases on the 3 position of the inositol ring. The PH domain in a number of proteins binds to PtdIns(3,4)''P''2 including the PH domain in PKB. The generation of PtdIns(3,4)''P''2 at the plasma membrane upon the activation of class I PI 3-kinases and SHIP phosphatases causes these proteins to translocate to the plasma membrane, thereby affecting their activity. == References == 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Phosphatidylinositol 3,4-bisphosphate」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.